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Is Citalopram Safe During Pregnancy?

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Citalopram
( R )-(−)-citalopram (top), ( S )-(+)-citalopram (bottom)
Clinical data
Pronunciation/ s aɪ ˈ t æ l ə ˌ p r æ m, s ɪ -/ ; [1]
Trade namesCelexa, Cipramil, others (see below)
AHFS/Drugs.comMonograph
MedlinePlusa699001
Pregnancy categoryUS: C (Risk not ruled out)
Routes of administrationOral
ATC codeN06AB04 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability80% peak at 4 h [2]
MetabolismLiver (CYP3A4 and CYP2C19)
MetabolitesDesmethylcitalopram (DCT) and didesmethylcitalopram (DDCT)
Elimination half-life35 h
ExcretionMostly as unmetabolized citalopram, partly DCT and traces of DDCT in urine

However, more studies have to be conducted for conclusive results. This can be done by prescribing a single medication monotherapy at the lowest effective dose, particularly during the first trimester. In addition, monoamine oxidase inhibitors MAOIs — including phenelzine Nardil and tranylcypromine Parnate — are generally discouraged during pregnancy.

Some studies suggested that babies whose mothers take SSRIs like citalopram or escitalopram during the third trimester might have a small increased chance for persistent pulmonary hypertension of the newborn PPHNhowever, other studies have not. Should I switch medications? A total of women took citalopram at least in the first trimester.

As for the role of a father, there does not seem to be any increased risk for the development of the baby if the father has been using Citalopram, either before or around the time you became pregnant.

PPHN is a serious lung problem. A total of women took citalopram at least in the first trimester.

Psychiatrist Katie Hirst discusses use of antidepressants in pregnancy

PPHN is a serious lung problem. So, there is nothing to worry about there. Citalopram use in pregnancy: Mothers, who take Citalopram 12 months before the delivery of the child, are at an increased risk of having a child with Autism Spectrum Disorder.

Journal information: The child may need a heart transplant to survive, as it can result in sudden death.

However, in opposition to this, studies on pregnant women brought evidence that there was no emergence of malformative neonatal toxicity. Despite being good in the treatment of depression, Celexa is a potent drug and can take a drastic turn if not administered properly.

Serotonin and norepinephrine reuptake inhibitors SNRIs. Some women remain well after stopping their antidepressant medication during pregnancy. The use of SSRIs by pregnant mothers can increase the odds of having a child with craniofacial and cardiac malformations, among other defects.

Babies exposed to any SSRI may have breathing problems, jitteriness, increased muscle tone, irritability, problems sleeping, tremors and difficulty feeding. References Available By Request.

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The purpose of this study was to investigate whether citalopram is associated with an increased incidence of adverse pregnancy outcomes. The scans revealed that babies in the SSRI group had "significant" increases in the size of amygdala and insula gray mattercompared with those born to mothers who had been diagnosed with depression can you take celexa while pregnant not given an SSRI and those born to moms without depression.

In general, exposures that fathers have are unlikely to increase risks to a pregnancy. Studies in animals found that citalopram might have caused some reduced fertility.

Problems breathing. There are still controversies regarding whether septal heart defects have risen to children whose mothers were prescribed this SSRI during early pregnancy.

These morphological alterations did match with human case studies, leading to the conclusion that use of Citalopram during pregnancy is related to birth defects and hence, is not safe for pregnant mothers. It is not known if taking citalopram or escitalopram will make it harder to get pregnant.

The use of SSRIs by pregnant mothers can increase the odds of having a child with craniofacial and cardiac malformations, among other defects. Author information: Though this affects just one baby out of every newborns, it can be serious. However, there's no evidence that discontinuing or tapering dosages near the end of pregnancy reduces the risk of these symptoms for your newborn.

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Can you take celexa while pregnant

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The specific brain regions in question are critical to the processing of emotions. Late pregnancy use of citalopram is associated with increased risk of poor neonatal adaptation syndrome, recently described with other selective serotonin reuptake inhibitors. There is not yet enough evidence showing the use of Citalopram linked to increased risk of stillbirth. Probably not.

Still, Cha noted that the study "does not demonstrate cause and effect. Since it is very similar to citalopram, escitalopram is also unlikely to increase the chance of birth defects over a background risk. If you are taking citalopram or escitalopram at the end of your pregnancy, your baby may need some extra care for the first few days of life. Antidepressants are a primary treatment option for most types of depression.

Since it is very similar to citalopram, escitalopram is also unlikely to increase the chance of birth defects over a background risk. Therefore, the use of Citalopram is now regarded as a matter of concern.

The scans indicated that SSRI exposure in the womb was associated with an increase in the size of gray matter found in two parts of the brain: If you use antidepressants during pregnancy, your health care provider will try to minimize your baby's exposure to the medication.

Which antidepressants should be avoided during pregnancy?

Can you take celexa while pregnant
She may also experience a premature delivery The decision to continue or change your antidepressant medication will be based on the stability of your mood disorder Escitalopram is used to treat depression and generalized anxiety disorder After delivery Common antidepressants in pregnancy may alter fetal brain developmentApril 10 retrieved 4 April from https
SSRI group infants also had "a significant increase" in white matter connections between those two regions However The scans indicated that SSRI exposure in the womb was associated with an increase in the size of gray matter found in two parts of the brain Why is treatment for depression during pregnancy important?Use of these medications during the second or third trimester might also be linked with postpartum hemorrhage

Can you take celexa while pregnant

There was a relative risk of 4. She may also experience a premature delivery.

Hypoplastic Left Heart Syndrome: If you are taking citalopram or escitalopram at the end of your pregnancy, your baby may need some extra care for the first few days of life. A structured telephone follow-up interview was conducted following the expected date of confinement. In the meantime, what should pregnant women struggling with depression do?

For other women, stopping their medication can be more harmful than the risks of staying on it. Cha noted that while maternal depression with or without SSRI treatment was accounted for, the study did not examine other critical factors that could affect fetal development, including a family history of depression.

Are antidepressants an option during pregnancy? For other women, stopping their medication can be more harmful than the risks of staying on it. Which antidepressants should be avoided during pregnancy? The exposed women were matched to a disease-matched group of women and a nonteratogenic group.

Despite being good in the treatment of depression, Celexa is a potent drug and can take a drastic turn if not administered properly. The drug escitalopram contains the same active medication as citalopram.

Persistent Pulmonary Hypertension: The concern is based on a new analysis of brain scans involving nearly newborns, some of whom were born to mothers who took selective serotonin reuptake inhibitors SSRIs while pregnant.

But there are benefits and risks to consider when taking antidepressants during pregnancy. When the study was conducted in a controlled laboratory setting, some of the craniofacial changes that were witnessed included flattening of the midface, reduction in the prominence of the upper jaw, a depressed nasal bridge and others.

Though this affects just one baby out of every newborns, it can be serious. Studies on animals can you take celexa while pregnant that high doses of Citalopram in pregnancy are linked to embryofetal toxicity and have negative effects on postnatal development of the child.

However, in opposition to this, studies on pregnant women brought evidence that there was no emergence of malformative neonatal toxicity. However, there's no evidence that discontinuing or tapering dosages near the end of pregnancy reduces the risk of these symptoms for your newborn.

Use of these medications during the second or third trimester might also be linked with postpartum hemorrhage.

These symptoms are usually mild and should go away by two weeks of age. Some research suggests that paroxetine might be associated with a small increase in fetal heart defects. Studies on animals concluded that high doses of Citalopram in pregnancy are linked to embryofetal toxicity and have negative effects on postnatal development of the child.

As for the role of a father, there does not seem to be any increased risk for the development of the baby if the father has been using Citalopram, either before or around the time you became pregnant.

This can cause organ failure and hence, poses a serious problem. Use of Citalopram during the first trimester of pregnancy was associated with an increased risk of the baby developing neural tube defect, including spina bifida. Of live-born infants whose mothers were exposed to citalopram in the first trimester, there was 1 0.

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Celexa, 4 reviews:

Comment №1 about product

Get the facts about antidepressant use during pregnancy.


5 / 5 stars
Comment №2 about product

Despite being good in the treatment of depression, Celexa is a potent drug and can take a drastic turn if not administered properly.


3 / 5 stars
Comment №3 about product

Taking medications during pregnancy can have risks and benefits. MAOIs might limit fetal growth.


2 / 5 stars
Comment №4 about product

If you stop taking antidepressants during pregnancy, you risk a depression relapse with associated complications including worsening mood, the inability to take care of yourself or your pregnancy, and postpartum depression or postpartum psychosis.


1 / 5 stars
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