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Isotretinoin
Clinical data
PronunciationSee note at tretinoin
Trade namesAccutane (originator), subsequently many generics [1]
AHFS/Drugs.comMonograph
MedlinePlusa681043
License dataUS   FDA: Isotretinoin
Pregnancy categoryAU: X (High risk) US: X (Contraindicated)
Routes of administrationBy mouth, topical
ATC codeD10AD04 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
BioavailabilityVariable
Protein binding99.9%
MetabolismHepatic
Elimination half-life10–20 hours
ExcretionRenal and fecal

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Accutane, 4 reviews:

Comment №1 about product

If the RMA expires before the prescription is picked up from the pharmacy, the patient must go back to their prescriber and start the authorization process again.


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The isotretinoin manufacturers have informed FDA that, during this time, their website will be completely unavailable.


3 / 5 stars
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The defendant, in order to prove that any concern or connexion which he had with the said Hatch and Kirkner, in the making of watch-chains, by means of the said machine, was merely as a purchaser of watch-chains from them under the following contract, produced and gave the same in evidence.


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